Radiotherapists 2018-03-08T21:07:28+00:00

Helping radiotherapists
accurately measure dosage

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The Technology

A unique high performance thermoluminescent detector (TLD) array consisting of 100+ small (1mm) micro silica glass beads packed on a wire for use in a standard catheter. The beads are able to detect radiation levels over 100 points in the patient’s body, giving clinicians an exact measurement of where, and how much, radiation the patient has received.

After the radiotherapy session, the radiation levels and spread will be measured by our fully automated high-performance thermo-luminescent reader. The results will be ready, typically, after 15 minutes, and are a unique “radiation ruler” or profile of radiation measurements along or across the tumour area and beyond. The software will compare the readings with the clinician’s plan and distribute the results.

Current Problems with Radiotherapy

Allow clinicians to see and measure where radiation hits inside the patient’s body

Radiotherapy in Practice

Radiotherapy clinicians carefully calculate and pre-test radiation treatment for each cancer patient. For external beam therapy the calculated radiation beams are directed at the tumour from the best and safest angles. Great care is taken to minimise hitting the surrounding healthy tissue and especially the patient’s critical organs. But, despite all the care, between 10% and 25% of radiotherapy patients worldwide suffer serious side effects or treatment failure.

One problem is how to directly measure the actual  radiation dose delivered into the patient’s body during radiotherapy. And that includes in brachytherapy when radiation sources are inserted into the patient. Today no one can see what the radiation hits or if it hits solely according to the clinician’s plan. No one knows the effects until the patient reports problems some weeks later.

TRUEinvivo bead array detectors are easily inserted via a catheter into a suitable natural orifice and measure the dose and spread of the radiation received at the site of the tumour.  A clinician can use this “radiation ruler” to check for accuracy against the plan immediately after the first patient session and, if necessary, adjust for the next dose. This test and correction for accuracy gives the clinicians real confidence that the correct dose has been given and in the correct places. More confidence can lead to less sessions.

The patient and clinicians still wait a few weeks to see if the cancer is cured but the wait is with the confident knowledge that the treatment was really accurate and that side effects and harm have been minimised.

Micro Silica Bead TLD Array

TRUEinvivo Microsilica Bead Thermoluminescent Dosimetry Material consists of Silicon Oxide. It is suitable for medical physics, research, and industrial dosimetry applications that use X, γ, β, proton and neutron radiations.

Bead Specifications
Product size 1mm/2mm/3mm Calibrated and screened TLDs, ±3% (k=2)
Accuracy Uncalibrated TLDs, ±8% (k=2)
Description Spherical bead with a hole in the middle, capable of arrangement in 2 or 3 dimensions
Material Silicon dioxide (SiO2:Na. Ca. Al. K)
Measurement ranges 1mGy to 100Gy (not yet tested for higher doses)

Product Features

  • High spatial resolution (1-3 mm)
  • Accurate and precise (± 1.7%)
  • Linear response over wide dynamic range (1mGy to 100Gy; not yet tested for higher doses)
  • No dose rate dependency
  • No directional dependency
  • Non-hygroscopic / inert nature
  • Suitable for use in aqueous environment e.g. invivo situations/in the water tanks
  • Readout and handling convenience
  • Small spherical shape with hole in the middle enables the TLDs to be threaded on a piece of wire and keep the sequence of TLDs during readout and annealing. A holder tray is not required! A vacuum tweezer is not required as the TLD can be easily handled using plastic/metallic tweezers.
  • Reusable
  • Robust
  • Can be used in extreme conditions of humidity and temperature

Estimated to save 9,000 patients annually just in the UK

Who is working with us?

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TRUEinvivo improves cancer care worldwide!

To find out more about how TrueInvivo technology is being implemented in hospitals around the country, please get in touch.
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